* It's an X-linked recessive hereditary disease [ dna; inherited] characterised by abnormally low levels of glucose-6-phosphate dehydrogenase a metabolic enzyme involved in the pentose phosphate pathway, especially important in red blood cell metabolism.
[G6PD -a cytosolic enzyme in the pentose phosphate pathway a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage;Of greater quantitative importance is the production of NADPH for tissues actively engaged in biosynthesis of fatty acids and/or isoprenoids, such as the liver, mammary glands, adipose tissue(fat), and the adrenal glands(They are chiefly responsible for releasing hormones in conjunction with stress ). ]
*G6PD is widely distributed in many species from bacteria to humans.
*causes acute hemolytic anemia in the presence of simple infection, ingestion of fava beans, or reaction with certain medicines, antibiotics, antipyretics, and antimalarials.
[[* It's similar to the deficiency named " Hemolytic anemia" ( anemia is a decrease in the number of red blood cells, or or a less than normal quantity of hemoglobin in the blood; and hemoglobin is the iron-containing oxygen-transport metalloprotien in the red blood cells of all vertebrates ; Hemolosis is the rupturing of red blood cells and the release of hemoglobin into surrounding fluid (e.g., blood plasma).]
Hemolytic anemia is the abnormal breakdown of red blood cells either in the capillaries or elsewhere in the body .It has numerous possible causes, ranging from relatively harmless to life-threatening.]]
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